http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110526928-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-18 |
| filingDate | 2019-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110526928-B |
| titleOfInvention | Refining method of 7-aminodesacetoxycephalosporanic acid |
| abstract | The invention provides a refining method of 7-aminodesacetoxycephalosporanic acid, which comprises the following steps: adding the 7-aminodesacetoxycephalosporanic acid crude product into water, uniformly dispersing, and adding ammonia water to adjust the pH value to 7.8-8.0 to obtain an alkali solution; adding sulfuric acid into the alkali dissolving solution, and adjusting the pH to 0.7-0.9 to obtain an acid dissolving solution; adding ammonia water into the acid solution, adjusting the pH to 7.8-8.0, and adding alcohol to obtain a to-be-crystallized solution; adding sulfuric acid into the solution to be crystallized under the condition of stirring at the temperature of 20-70 ℃, adjusting the pH to 3.8-4.0, and growing crystals for 6-60min to obtain the 7-aminodesacetoxycephalosporanic acid product. The purity of the 7-ADCA prepared by the refining method provided by the invention can reach more than 99.91%, the yield is more than 87%, the content of delta-2-7-ADCA is less than 0.06%, and the method has a wide application prospect. |
| priorityDate | 2019-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 38.