http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110526895-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-56 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-56 |
filingDate | 2018-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-110526895-B |
titleOfInvention | Preparation and separation method of raloxifene dimer |
abstract | The invention discloses a preparation and separation method of raloxifene dimer. Raloxifene hydrochloride is used as a raw material, and is polymerized under the action of hydrogen peroxide, alkyl diamine and ferric trichloride to generate a crude product of raloxifene dimer; and purifying the raloxifene dimer crude product by preparative chromatography to obtain a raloxifene dimer refined product. The preparation method and the separation method of the raloxifene dimer have the advantages of simplicity in operation, environmental friendliness, low cost and high purity of the obtained dimer, and lay a good foundation for the quality research and control of the raloxifene. |
priorityDate | 2018-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 44.