| abstract |
The present disclosure provides metal-organic framework-based hybrid nano-drug delivery system and its preparation method and application. The metal-organic framework-based hybrid nano-drug delivery system includes targeted functional materials, metal-organic framework materials and active drug materials, and the active drug materials are loaded on In the pores of the metal organic framework material, the surface of the metal organic framework material is loaded with targeting functional materials, and the active pharmaceutical material is one or more of photothermal conversion agents, adjuvants, and immunomodulators, and the targeting function The material is hyaluronic acid and/or mannan. Accurate, safe and efficient anti-tumor therapy is realized through the metal-organic framework-based hybrid nano drug delivery system provided by the present disclosure. |