http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110506124-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_49f9482d0ae56f3c77198101cae760a9 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2563-179 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2563-131 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2525-131 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2521-531 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2565-1015 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2525-301 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2537-162 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2565-201 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1055 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6804 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6845 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6804 |
| filingDate | 2018-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4fed722b70fa941c65018ef26e34fe8b |
| publicationDate | 2019-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110506124-A |
| titleOfInvention | Method for determining the level of interaction between biomolecules |
| abstract | The present invention relates to a method for determining the level of interaction between biomolecules such as proteins in a sample, comprising providing first and second information-carrying (IC) oligonucleotides, wherein the first and second IC oligonucleotides The nucleotides are covalently or non-covalently attached to first and second affinity reagents such as antibodies having the ability to bind to the first and second biomolecules, wherein the first and second IC oligonucleotides each comprise at least one single-stranded segment complementary to a portion of the other oligonucleotide such that the at least one single-stranded segment in at least one of the first and second IC oligonucleotides is complementary to the other oligonucleotide Following hybridization of their complementary moieties, the relative proportions of the interacting first and second biomolecules to the non-interacting first and second biomolecules in the sample can be measured at the single cell level or at the single molecule level. Furthermore, the present invention relates to kits comprising oligonucleotides and reagents necessary for carrying out the methods of the present invention. |
| priorityDate | 2017-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 133.