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filingDate 2019-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-110499266-B
titleOfInvention Enterococcus faecalis and application thereof
abstract The invention relates to enterococcus faecalis capable of separating virulent phage of enterococcus faecalis and application thereof, and belongs to the field of bioengineering. The bacteria is preserved in China Center for Type Culture Collection (CCTCC) NO of M2019275, and the preservation date is 2019, 4 and 19 days, and is isolated from the root canal of department of stomatology of Yanan Hospital, university of Kunming medical science. In the invention, the transmission electron microscope observes that the bacteria have no spores and flagella and the diameter is 0.9-1.1 mu m. The growth temperature range is 20-42 deg.c, and the optimal temperature is about 37 deg.c. The growth cycle is divided into four stages of slow phase, logarithmic phase, stationary phase and decay phase, and the logarithmic phase is maintained at 160-240 min. The enterococcus faecalis can be used for separating virulent phages aiming at the enterococcus faecalis; meanwhile, the strain is used as an infection source to establish an SD rat enterococcus faecalis abdominal cavity infection model and a southern Yunnan small-ear enterococcus faecalis infected periapical inflammation model, so that the strain can be comprehensively used for evaluating the enterococcus faecalis infection and treatment.
priorityDate 2019-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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