http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110498835-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-06 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06 |
filingDate | 2018-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-110498835-B |
titleOfInvention | ETELCALCETIDE synthesis method |
abstract | The invention relates to a method for synthesizing Etelcalcetide, which comprises the following steps: 1) synthesizing a compound 3; 2) synthesis of polypeptide resin by solid phase Synthesis: H-D-Ala-D-Arg (Pbf) -D-Ala-D-Arg (Pbf) -solid phase synthesis resin; 3) coupling the compound 3 obtained in the step 1) and the polypeptide resin obtained in the step 2) to obtain; 4) and (3) cracking the peptide resin and removing the protecting group at the same time to obtain the Etelcalcetide. The method does not use mercaptopyridine compounds in the synthesis process, is more environment-friendly and has higher synthesis efficiency. |
priorityDate | 2018-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 134.