http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110498730-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C209-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C303-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C201-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C201-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C17-35 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C17-35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C303-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C201-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C201-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C209-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C307-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C205-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C25-13 |
| filingDate | 2019-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110498730-B |
| titleOfInvention | Synthetic method of 1,2, 4-trifluorobenzene |
| abstract | The invention provides a synthesis method of 1,2, 4-trifluorobenzene, and belongs to the field of preparation of pesticide, medicine and liquid crystal material intermediates. The method solves the problems of harsh reaction conditions and the like of the existing synthesis of the 1,2, 4-trifluorobenzene, and is characterized by comprising the following steps: 2, 4-dichloro fluorobenzene is taken as a raw material, nitric acid is taken as a nitration reagent, and 2, 4-dichloro-5-fluoronitrobenzene is generated by nitration in the presence of sulfuric acid; dissolving 2, 4-dichloro-5-fluoronitrobenzene in an organic solvent, adding potassium fluoride and a first catalyst, and fluorinating under the catalysis of the first catalyst to obtain 2,4, 5-trifluoronitrobenzene; dissolving 2,4, 5-trifluoronitrobenzene in a solvent, and hydrogenating and reducing the solution with hydrogen under the catalysis of a second catalyst to obtain 2,4, 5-trifluoroaniline; the 2,4, 5-trifluoroaniline firstly reacts with sulfuric acid, then reacts with nitroso-sulfuric acid for diazotization after salification, then reacts with sodium hypophosphite for deamination reduction under the catalysis of copper salt, and finally 1,2, 4-trifluorobenzene is obtained through steam distillation. The invention has the advantages of mild reaction conditions and the like. |
| priorityDate | 2019-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 81.