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filingDate 2019-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e9594a2ea1c12d6c4e3bfaddbd3ff02
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publicationDate 2019-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-110496222-A
titleOfInvention The purposes of people's NCAPH gene
abstract The invention discloses a kind of new applications of people's NCAPH gene, i.e., in screening and prepare the application in treatment Head and neck squamous cell carcinoma by action target spot of people NCAPH gene, NCAPH expresses high compared in normal tissue in Head and neck squamous cell carcinomaï¼›Expression is higher, and patient's life span is shorter, and the patient of low expression, and life span is relatively longï¼›Experimental result, which is shown in cancer cell, reduces NCAPH expression, the proliferation of nasopharyngeal carcinoma cell can obviously be inhibited, make cell block in the G2/M phase, the apoptosis for promoting cell, the migration for inhibiting cell, the formation for inhibiting xenograft tumours, and then it can achieve the purpose that treat nasopharyngeal carcinoma, NCAPH strikes low expression simultaneously, nasopharyngeal carcinoma cell can be dramatically increased to the sensibility of radiotherapy, the present invention provides possibility for the exploitation of the Head and neck squamous cell carcinoma therapeutic agent based on NCAPH gene, and can guiding clinical treatment, have biggish application value and prospect.
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