abstract |
The present invention provides pharmaceutical compositions containing the following compounds having antiviral effects. P is a hydrogen atom or a group forming a prodrug; A 1 is CR 1A R 1B , S or O; A 2 is CR 2A R 2B , S or O; A 3 is CR 3A R 3B , S or O; A 4 Each independently is CR 4A R 4B , S or O; wherein, the ring formed by A 1 , A 2 , A 3 , A 4 , a nitrogen atom adjacent to A 1 , and a carbon atom adjacent to A 4 The number of heteroatoms forming ring atoms is 1 or 2; R 1A and R 1B are each independently hydrogen, halogen, or alkyl, etc.; R 2A and R 2B are each independently hydrogen, halogen, or alkyl, etc. R 3A and R 3B are each independently hydrogen, halogen, or alkyl, etc.; R 4A and R 4B are each independently hydrogen, halogen, or alkyl, etc.; R 3A and R 3B optionally together form a non-aromatic carbon Ring or non-aromatic heterocycle; R 1 is a fluorine atom; m is an integer of 1-2, and n is an integer of 1-2. |