http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110483573-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2021-6417 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1029 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1014 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1007 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1025 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6456 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-65586 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6486 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-33 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6558 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06 |
| filingDate | 2019-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110483573-B |
| titleOfInvention | A kind of mitochondria-targeted hypochlorous acid ratio type two-photon fluorescent probe and its preparation method and use |
| abstract | The invention discloses a mitochondria-targeting hypochlorous acid ratio type two-photon fluorescent probe and a preparation method and application thereof. The mitochondria-targeting hypochlorous acid ratio type two-photon fluorescent probe is based on carbazole as a parent body, and its The structure is as follows: When the fluorescent probe of the invention is applied to the detection of HClO in an aqueous solution, the selectivity is high, the response speed is fast, the probe fluorescence ratio (I 525nm /I 465nm ) has a good linear relationship with the concentration of HClO, and the detection limit is as low as 35nM . In addition, the fluorescent probe molecule also has excellent two-photon absorption properties. Cytotoxicity tests showed that the probe had little toxic side effect on cells. Two-photon confocal fluorescence microscopy experiments show that the probe has good mitochondrial localization ability and cell membrane permeability, and is suitable for two-photon fluorescence imaging and quantitative detection of HClO in cell mitochondria. |
| priorityDate | 2019-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 66.