http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110483386-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3e9f6642b676dd0ffc88759a1108a9f1 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1029 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0021 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K11-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 |
| filingDate | 2019-09-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_abfd6ead732d3359934760ecbd582f23 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ce620f336960f6779fefcb5dd24286d |
| publicationDate | 2019-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110483386-A |
| titleOfInvention | A kind of superoxide anion probe and its preparation method and application |
| abstract | The invention discloses a superoxide anion probe and its preparation method and application, and specifically relates to the field of medical imaging, including a superoxide anion probe whose structural formula is as follows: Its raw material compound structural formula is respectively: and The present invention uses 2-(2'-pyridiniminomethyl)pyridine (2-APC) as a fluorescent probe, and pyrogallol autoxidation system as a source of superoxide anion, and utilizes 2-APC to generate fluorescence with superoxide anion Based on the principle that the fluorescence intensity of the reaction system is significantly reduced by quenching the reaction, a method for the determination of the relative concentration of superoxide anion and protocatechuic acid and the clearance rate of superoxide anion has been established, which is easy to operate, high in sensitivity and good in stability, and can be better Remove the superoxide anion and reduce the damage caused by the superoxide anion in the superoxide anion probe to the patient's matrix. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114456079-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114456079-B |
| priorityDate | 2019-09-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 46.