| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01J2001-4453
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-4738
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2201-0625
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B2560-0228 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01J3-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01J1-0488
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0004
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6486
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01J3-4406
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6408
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-645
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01J3-027
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-7228
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01J1-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-4738
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01J1-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0021
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01J3-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-201
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-0071 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-25
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01J1-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01J1-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B30-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01T1-10 |
| filingDate |
2018-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2022-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2022-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-110476051-B |
| titleOfInvention |
A non-invasive monitoring method of fluorescent tracers with background separation correction |
| abstract |
Disclosed is a method of monitoring time-varying fluorescence emitted from a fluorescent agent within a diffusely reflective medium having time-varying optical properties, the method comprising providing at least two measurements obtained from a patient before and after administration of the fluorescent agent, the Measurements include a Flr meas signal adjacent to the medium detected by a filtered photodetector during illumination of the medium with excitation wavelength light, and at least one DR signal selected from: DR em and DR em, filtered signals. The method also includes identifying the post-equilibrium portion of the measurement data set, and converting each Flr meas signal within the post-equilibrium portion of the measurement data set to an IF agent signal representing only emission from the fluorophores within the medium Detected fluorescence intensity. The disclosed method includes eliminating the effect of leakage of excitation-level light and eliminating the effect of autofluorescence from the Flr meas signal. |
| priorityDate |
2017-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |