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filingDate 2019-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-110470688-B
titleOfInvention Nano chelating sieve mediated low-field nuclear magnetic resonance immunosensor and application thereof
abstract The invention discloses a nano chelating sieve mediated low-field nuclear magnetic resonance immunosensor and application thereof, and belongs to the field of food safety analysis and detection. The immunosensor comprises a complete antigen or a capture antibody-polystyrene microsphere-polyglutamic acid, a magnetic bead-antibody, polystyrene microsphere-azide and magnetic particles-alkyne. The sensor is prepared into a nano chelating sieve based on chelating chemical reaction, specifically adsorbs copper ions, further controls the degree of copper ions catalyzing click chemical reaction, realizes signal reading and amplification of the low-field nuclear magnetic resonance immunosensor, has the characteristics of high sensitivity, strong specificity and the like, and can realize detection of various small molecular target objects including pesticides, antibiotics and biomacromolecules.
priorityDate 2019-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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