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filingDate 2019-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-110468143-B
titleOfInvention Preparation method and application of antibacterial peptide NZX
abstract The invention provides a preparation method and application of antibacterial peptide NZX. According to the invention, by optimizing the gene sequence of the antimicrobial peptide NZX, the efficient expression of the antimicrobial peptide NZX in pichia pastoris is realized for the first time, the yield is in the way of overcoming the gram level, the problems of too low yield or too high chemical synthesis cost in large-scale production are solved, a perfect purification system is established, and the large-scale production can be realized. In addition, an antibacterial experiment result shows that the antibacterial peptide NZX has obvious antibacterial activity on gram-positive bacteria, has the characteristics of low cytotoxicity and low hemolysis, can be applied to the fields of antibacterial drug development, feed additive development and the like, and has wide application value and market prospect.
priorityDate 2019-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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