http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110467556-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-584 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-46 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-46 |
| filingDate | 2019-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110467556-B |
| titleOfInvention | A kind of nucleophilic reaction method of nickel-catalyzed imide ion and acetophenone |
| abstract | The invention relates to a nucleophilic reaction method of nickel-catalyzed imide ions and acetophenone, wherein 3-hydroxy-2-phenethyl-isoindoline-1-ketone compounds and acetophenone compounds are dissolved in an organic solvent , the Ni(II) compound catalyst was added and the reaction was stirred at 80-120 ° C for 4-8 h, the reaction solution after the reaction was extracted, the organic layers were combined, washed, dried, and the solvent was evaporated, and the residue was subjected to silica gel column chromatography, namely get product. The invention uses a divalent nickel compound as a catalyst, the reaction conditions are mild, the disadvantages of the strong acid catalytic system and harsh conditions of the traditional method are avoided, and the reaction yield is high. |
| priorityDate | 2019-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 56.