http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110464881-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J2201-0484 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J2201-0446 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J2389-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-227 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J9-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J9-26 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J9-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J9-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L89-00 |
| filingDate | 2019-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110464881-B |
| titleOfInvention | Silk fibroin porous scaffold with hierarchical structure and preparation method thereof |
| abstract | The invention discloses a preparation method of a fibroin porous scaffold with a hierarchical structure, which uses an acid-salt binary solution system to rapidly dissolve degummed fibroin fibers; adding sodium chloride particles serving as a pore-foaming agent into the fibroin solution; then, carrying out soaking water treatment, wherein acid in a silk fibroin dissolving system is quickly diluted in water to change the pH value of the system so as to induce the silk fibroin solution to be gelatinized, and sodium chloride is slowly dissolved in water to generate a space to form a silk fibroin macroporous framework; adding a pure silk fibroin solution into a silk fibroin macroporous frame, and performing an electrostatic field effect to regulate and control the arrangement direction and the size of silk fibroin injected into the silk fibroin macroporous frame to form the silk fibroin porous bracket with a micro-nano hierarchical structure. The preparation method is green and efficient, the prepared fibroin porous scaffold simulates the physical microenvironment of cell growth, is environment-friendly and good in biocompatibility, and can be used as a biomedical carrier and a tissue engineering repair material. |
| priorityDate | 2019-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 37.