| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dc501dfe6278fb44df47a4b94c29b57a |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-658
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N1-34 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N1-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-65 |
| filingDate |
2019-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d078b10bb7a5718d9f36f8c42a61f93
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eba917aa4186593292938d709d38e551
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9256d29da8f917cc5dc779c108893de0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d932283ba39f41c572618027a136ab73
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_af41456a68320eec782518a7d5029d38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b17cc5f848c9879b0797f8aa0fb0310
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c821905092d318c4ec2c1a842d47e11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f776cfb42897f113412f51920ff64684 |
| publicationDate |
2019-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-110455777-A |
| titleOfInvention |
A novel method for the detection of creatinine in urine based on surface-enhanced Raman spectroscopy |
| abstract |
The present invention particularly relates to a novel method for detecting creatinine in urine based on surface-enhanced Raman spectroscopy, comprising the following steps: (A) taking normal urine and urine to be detected, and removing urea in the urine; (B) removing urea from the urine; Creatinine powder was added to normal urine after urea to make standard concentration creatinine samples; (C) SERS substrate synthesis; (D) SERS spectrum after collecting creatinine samples and removing urine to be tested on the SERS substrate. The spectral data is processed to obtain the creatinine concentration in the urine to be detected. By removing urea in urine, the strong adsorption of ‑NH2 group of urea to SERS-enhancing substrate gold/silver particles can be avoided, which hinders the adsorption of creatinine molecules in urine, thereby eliminating the presence of a large amount of urea in urine SERS detection. The competitive effect of creatinine improves the Raman response of creatinine in urine, and the detection sensitivity is high. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112098391-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112116975-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112098391-A |
| priorityDate |
2019-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |