| abstract |
The present application relates to polycyclic compounds having pyridone or pyridone derivative cores including substituted pyridones, 5,6-bicyclic heterocycles and 6,6-bicyclic heterocycles rings, and substituted pyridine-thiones. Also disclosed herein are methods of making such polycyclic compounds, pharmaceutical compositions and medicaments comprising the compounds, and methods of treating, preventing or diagnosing diseases, disorders or conditions associated with fibrosis. |