http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110438230-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3b363e79904ec95870df0e529efd1b34 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-166 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6886 |
| filingDate | 2019-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c487567d3ce2a92ad5c7a51deec4100 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b04fa5e3335aa5d395c68bccf3299073 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_73cf1e8e1f879ebdc2d6a643ddde1858 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_15ff652b5c0d639a56fe9ec7be9b0e3e |
| publicationDate | 2019-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110438230-A |
| titleOfInvention | NTRK fusion mutation standard and preparation method and application thereof |
| abstract | The invention relates to an NTRK fusion mutation standard product and a preparation method and application thereof. The method comprises the following steps: analyzing the relationship between NTRK fusion gene types and tumors; designing sequence information of different NTRK fusion mutations; The NTRK fusion sequence was stably integrated into the genome of the cell; the cells were cultured and lysed, then RNA was extracted and the concentration and purity of the RNA were detected; according to the target sequence, primers and probes were designed, and sanger sequencing and DdPCR were used to verify the identity of the target sequence. Fusions, and corresponding copy number information; design different experimental groups to verify the stability and specificity of the standards. The preparation method of the NTRK fusion mutation standard product of the present invention is suitable for multi-purpose detection means and has good commercial and clinical prospects. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110714065-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113106149-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110714065-B |
| priorityDate | 2019-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.