http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110437236-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 |
| filingDate | 2019-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110437236-B |
| titleOfInvention | Indole-1, 2-and 1, 4-benzodiazepine compound and synthetic method thereof |
| abstract | The invention discloses a synthesis method of indole-1, 2-and 1, 4-benzodiazepine compounds, belonging to the technical field of chemical synthesis. The indole-1, 2-and 1, 4-benzodiazepine compound is prepared through serial N-alkylation, dehydration and reaction of [1,5]]Initiation of redox-neutrality [5+2] of 3-alkylindoles with o-aminobenzaldehydes by processes such as hydride transfer and Friedel-Crafts alkylation]And (4) cyclization reaction. The method rapidly constructs a novel indole skeleton-containing cyclic compound through hydrogen migration/cyclization tandem reaction, has less self-cyclization reaction of aldehyde, and activates inert C (sp) through hydrogen migration 3 ) the-H bond has the characteristics of simplicity, greenness, high efficiency and the like, the conditions are simple, the reaction is rapid, and the generated byproduct is water, so that the method is green and environment-friendly. |
| priorityDate | 2019-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 112.