abstract |
The present invention relates to a bi-cyclic nucleocapsid inhibitor and its use as a medicine for treating hepatitis B. Specifically, the present invention discloses a compound having the structure shown in chemical formula A, or a stereoisomer or tautomer thereof, or a pharmaceutically acceptable salt, hydrate or solvent thereof, which can be used as an HBV inhibitor compound, the definition of each group is detailed in the description. The present invention also relates to pharmaceutical compositions comprising the above-mentioned compounds and their use in the treatment of hepatitis B. |