| abstract |
The clonazepam tablet comprises the following raw materials in parts by weight: 0.5-1.5 parts of clonazepam, 25-50 parts of first filler, 5-50 parts of second filler, 0.05-1.5 parts of adhesive, 0.05-1 part of first lubricant, 0.05-0.5 part of second lubricant and a proper amount of purified water; the first lubricant is talcum powder, and the second lubricant is magnesium stearate. The preparation process of the clonazepam tablet comprises the working procedures of raw material weighing preparation, material mixing, slurry preparation, wet granulation, granule finishing, total mixing, tabletting, packaging and the like. The preparation method is suitable for large-scale and industrial popularization and production, and the prepared product has better formability, dissolution rate and chemical stability and effectively improves the safety and effectiveness of medication. |