http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110404084-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0052 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-103 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-1857 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-128 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-1833 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y15-00 |
| filingDate | 2019-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110404084-B |
| titleOfInvention | DNA photo-thermal fusion-based nano particle, preparation method and application |
| abstract | The nanoparticle comprises a polydopamine inner core, a DNA double strand and a gadolinium salt chelate, wherein the DNA double strand is formed by hybridizing a DNA single strand 1 and a DNA single strand 2, one end of the DNA single strand 1 is connected with the polydopamine inner core through a chemical bond, and one end of the DNA single strand 2 is connected with a ligand of the gadolinium salt chelate through a chemical bond. The nano-particle can release the MRI contrast agent containing Gd after double-stranded DNA is melted through photothermal conversion, and the released MRI contrast agent can be rapidly discharged out of a body through renal metabolism, so that the potential toxicity problem caused by heavy metal ions in the in-vivo circulation time is greatly reduced. |
| priorityDate | 2019-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 44.