| abstract |
The present invention relates to the technical field of vitamin C injections, and specifically provides a method for controlling the oxidation resistance of vitamin C injections, including (1) quality control of raw material vitamin C and auxiliary materials; (2) cleaning and drying of ampoules; (3) Preparation: Add raw material vitamin C and auxiliary materials according to the prescription amount to prepare liquid medicine; (4) Fine filtration: 0.22μm microporous membrane cartridge filter; (5) Potting; (6) Sterilization: Sterilization conditions 100°C for 9 minutes, after sterilization, turn on the spray equipment to cool down the ampoule bottle. The present invention strictly controls the raw materials, adjusts and optimizes the process, and after the accelerated test and the long-term stability test of the vitamin C injection produced by the control method, all performances meet the standard requirements, which improves the quality of the product. Stability, optimized process production efficiency and finished product qualification rate have all been significantly improved. |