| abstract |
An ion exchange chromatography packing material is described that includes carrier resin particles and a copolymer grafted to the carrier resin particles. The copolymer includes polymerized functional monomers such as a first ion exchange group monomer and a second ion exchange group monomer. At the first pH, the first ion exchange group monomer is configured to have a first charge at the first pH, and the second ion exchange group monomer is configured to have a net neutral charge. At the second pH, the first ion exchange group monomer is configured to have a first charge at the second pH, and the second ion exchange group monomer is configured to have a charge at the second pH, wherein the first Both the charge and the second charge have the same polarity. |