http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110390995-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B15-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B50-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B50-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B15-20 |
| filingDate | 2019-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110390995-B |
| titleOfInvention | Alpha spiral transmembrane protein topological structure prediction method and device |
| abstract | An alpha helix transmembrane protein topological structure prediction method, which organizes a training set, a verification set and a test set according to the definition of transmembrane alpha helix TMH; extracting position specificity scoring matrixes PSSM, HMM, water solubility, secondary structure, torsion angle and hydropathic index characteristics from the sequences in the training set, the verification set and the test set; training the whole sequence-based depth residual error network model and the sliding window-based depth residual error network model using a training set. After the outputs of the two networks are averaged and integrated, a dynamic threshold algorithm is adopted to obtain a TMH area; the support vector machine model is trained using a training set. The input of the model is the boundary part of other regions non-TMH and TMH; the output is the position of non-TMH relative to the cell membrane. The TMH region in the protein is predicted, then the non-TMH position is predicted, and the final topological structure of the protein can be obtained by combining the prediction results of the two parts. |
| priorityDate | 2019-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 17.