http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110376260-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-3278 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N27-308 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-327 |
| filingDate | 2019-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110376260-B |
| titleOfInvention | Preparation method of photoelectrochemical aptamer sensor for detecting prostate specific antigen |
| abstract | The invention discloses a preparation method of a photoelectrochemical aptamer sensor for detecting prostate specific antigen. Loading a large number of cadmium sulfide quantum dots and a signal transduction probe with one end marked with a graphene quantum dot on a paper-based platinum/zinc oxide nano-sheet, activating a co-sensitization effect, and increasing a photocurrent signal; when the aptamer of the labeled gold nanoparticle for specifically recognizing the prostate specific antigen is hybridized with the signal transduction probe to form the three-strand helical molecular switch, the co-sensitization effect is inhibited, the signal quenching effect of the gold nanoparticle is generated, and the photocurrent signal is reduced; when the prostate specific antigen recognizes the aptamer, the three-strand helical molecular switch conformation changes, the co-sensitization effect is reactivated, the quenching effect is eliminated, and the photocurrent signal is enhanced; sensitive detection of prostate specific antigens is achieved based on the converted signal. |
| priorityDate | 2019-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 65.