http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110372688-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2002-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-4926 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D455-03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L33-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q19-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D455-03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4375 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-49 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L33-10 |
| filingDate | 2019-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110372688-B |
| titleOfInvention | 8-dihalomethylene dihydroberberine type compound and anti-infection and anti-inflammatory application thereof |
| abstract | The invention discloses an 8-dihalomethylene dihydroberberine type compound and anti-infection and anti-inflammatory application thereof, in particular to an 8-dihalomethylene dihydroberberine type compound shown as a general formula I, physiologically acceptable salts thereof, a synthetic method thereof and application thereof in preparing products for preventing, relieving and/or treating microbial infection and inflammation. Compared with the berberine type alkaloid quaternary ammonium salt substrate, the 8-dihalomethylene dihydroberberine type compound has obviously improved antibacterial activity on gram-positive bacteria and fungi; the compound has obvious anti-inflammatory activity on mouse ear acute swelling model animals caused by croton oil; the pharmacological action strength of the compound is obviously higher than that of a contrast medicament, and the compound has the advantages of no toxicity or low toxicity, and can be used for preparing products for preventing, relieving and/or treating microbial infection and inflammation. |
| priorityDate | 2018-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 228.