| abstract |
The invention relates to a synthesis method of a selenized benzofuran compound. In an organic solvent, under the condition of oxygen, aromatic boronic acid and selenium powder generate phenylselenyl free radicals in situ under the action of a silver catalyst, and further react with alkynyl benzyl The ether undergoes a free radical tandem cyclization reaction to obtain a selenide benzofuran compound. The invention also discloses the selenide benzofuran compound prepared by the above method. Alkynyl anisole raw materials are easy to synthesize, elemental selenium is cheap and easy to obtain, wide range of reaction substrates, good functional group tolerance, simple reaction conditions, high product yield and purity, and open up a new synthesis for selenized benzofuran compounds The route and method have good application potential and research value. |