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filingDate 2019-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-110368524-B
titleOfInvention Bioactive bone repair scaffold and preparation method thereof
abstract The invention discloses a bioactive bone repair scaffold and a preparation method thereof, the bioactive bone repair scaffold takes degradable polymer as a matrix and takes magnesium lithium silicate and magnesium as reinforcing phases, and the bioactive bone repair scaffold comprises the following components in percentage by mass: 5-15% of lithium magnesium silicate, 10-30% of magnesium and 55-85% of degradable polymer. The preparation method comprises the following steps: 1) preparing a magnesium lithium silicate hydrogel; 2) preparing a mixture; 3) preparing 3D printing raw material particles; 4) the bioactive bone repair scaffold is printed in 3D. The scaffold has the advantages that the internal and external structures can be designed in a customized manner, no organic solvent is added, the interface combination of multiple components is good, the requirement on the mechanical strength of cancellous bone (0.2-80 Mpa) can be met, the self-response slow release of functional ions induces the deposition of hydroxyapatite on the surface of the scaffold, the bone and cartilage injuries can be repaired in a synergistic manner, the individual customized preparation of the bioactive bone repair scaffold is realized, and the application prospect of the scaffold in the fields of rehabilitation treatment of the bone and cartilage injuries and the like is widened.
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