http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110368489-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_41ff4f7cbb1608ce93333ff57bf3ccba |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-552 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-521 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-145 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 |
| filingDate | 2019-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0fa6958c870c1d2cd060a7e43626ba8f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4399065883992bc90eb6f3c985024833 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_370b1370660af5fabd191bf14aa75ff8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2f27ce1b8fe8932bebbb43937c829bdc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_91322e2dfd79ec565f1ef8a42205ffc1 |
| publicationDate | 2019-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110368489-A |
| titleOfInvention | A kind of preparation method of monovalent inactivated vaccine of sheep fast epidemic disease |
| abstract | The invention relates to the technical field of veterinary microbiology, in particular to a preparation method of monovalent inactivated vaccine for sheep rapid epidemic. The preparation method of the rapid epidemic monovalent inactivated vaccine comprises: strain screening, strain cultivation, strain virulence verification and vaccine preparation. Clostridium putrefaciens of the present invention is a high-yielding toxin-producing deer-sourced Clostridium putrefaction (QH-FB01 strain) isolated from pastoral areas of the Qinghai-Tibet Plateau. The lethality of conventional culture to mice can reach 200MLD/ml. By optimizing the optimal toxin-producing conditions of the bacterial strain, Improvement of the medium formula can make the lethality of the Clostridium putrefaciens strain (QH‑FB01 strain) to mice reach an average of 1000MLD/ml, much higher than the 100MLD/mL virulence of conventional vaccine production strains, and through the optimization of culture conditions , so that the culture characteristics of the clostridium putrefaciens strain are relatively stable, the production cost is greatly reduced, and the production efficiency is improved. |
| priorityDate | 2019-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 38.