| abstract |
The invention relates to the field of medicines and cosmetics, in particular to a composition with an anti-pollution and anti-damage effect, and a preparation method and application thereof. The composition comprises the following raw materials in parts by weight: 1-24 parts of rhodiola rosea, 1-24 parts of galangal, 1-24 parts of ginkgo leaves and 1-24 parts of grape seeds. Experiments prove that the composition can regulate and control polycyclic aromatic hydrocarbon pathway related factors caused by benzopyrene and PM2.5 air pollution, reduce CYP1A1 expression, eliminate free radicals, reduce the level of Reactive Oxygen Species (ROS), repair oxidative damage, inhibit the generation of inflammatory factors IL-1B, and reduce the expression of matrix metalloproteinase MMP1, so that the composition can be applied to skin, respiratory tract and lung injuries caused by PM2.5 air pollution. |