http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110368374-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K33-243 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5169 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-555 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-555 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-243 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2019-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110368374-B |
| titleOfInvention | Anti-tumor platinum drug mineralized protein nanoparticles and preparation method and application thereof |
| abstract | The invention discloses an anti-tumor platinum drug mineralized protein nanoparticle and a preparation method and application thereof. The invention successfully prepares the platinum medicament mineralized protein nanoparticles by adopting a two-step preparation method for the first time, and the prepared nanoparticles are uniformly dispersed in an aqueous solution; the nanoparticles have good tumor cell toxicity effect, and IC of human non-small cell lung cancer cell A549 50 6.9. mu.g/ml. The platinum drug mineralized protein nanoparticles provided by the invention comprise platinum drugs and proteins, have the remarkable advantages of simple and convenient preparation process, uniform size, controllable particle size, good biocompatibility, good water solubility, long circulation time in blood, high tumor targeting property and the like, and lay a foundation for efficient tumor treatment and drug-resistant tumor treatment. |
| priorityDate | 2019-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 257.