http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110361458-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1de6b479f16033ad96da872b5669459b |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2030-027 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-02 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-02 |
filingDate | 2019-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2a76e11ffc46e88237e8280c3c903a21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f6d7fc4ec95ae71cabea42720525ec93 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e5a03dd65becfa7d1b88432684623c0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1782271153ad1f3cc68700de91216629 |
publicationDate | 2019-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-110361458-A |
titleOfInvention | A kind of determination method of guanine in ganciclovir |
abstract | The invention discloses a method for determining the content of guanine in ganciclovir, which belongs to the technical field of drug analysis and detection, and the detection method is high performance liquid chromatography. The phase chromatographic column has good peak shape, and can be completely separated from ganciclovir to facilitate quantitative analysis; the technical scheme of the present invention is characterized in that: n-hexane-isopropanol is used as the mobile phase, and cellulose-tris(4- Tolyl formate) silica gel as the filler, n-hexane-isopropanol (80:20) as the mobile phase, the flow rate is 0.8~1.5ml/min, the column temperature is 25~35℃, the detection wavelength is 252nm, The sample volume was 10 μL, and the isocratic elution was performed. The method of the invention is simple, reliable, high in sensitivity, good in resolution and reproducibility, accurate and reliable in results, and can be used for controlling the content of guanine in ganciclovir. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113834880-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113834880-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112858504-A |
priorityDate | 2019-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 48.