http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110358737-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-33 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-001102 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2803 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0636 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-7051 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2878 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
| filingDate | 2019-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110358737-B |
| titleOfInvention | Method for preparing chimeric antigen receptor T lymphocyte by using exosome |
| abstract | The invention provides a method for preparing chimeric antigen receptor T lymphocytes by using exosomes, which comprises the following steps: (1) obtaining T lymphocytes of a subject; (2) culturing the T lymphocyte, and extracting exosome; then continuing culturing the T lymphocyte to obtain a T lymphocyte culture A; (3) transfecting the exosome with a plasmid expressing an antigen chimeric receptor to obtain an exosome containing a CAR plasmid; (4) mixing and culturing the exosome containing the CAR plasmid in (3) and the T lymphocyte culture A in (2) to obtain the antigen chimeric receptor T lymphocyte. The invention also provides an exosome, an antigen chimeric receptor T lymphocyte prepared according to the method and application of the antigen chimeric receptor T lymphocyte in preparing a medicament for treating cancer. |
| priorityDate | 2019-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 34.