http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110343189-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0003 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-715 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-715 |
filingDate | 2019-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-110343189-B |
titleOfInvention | Durian peel polysaccharide, extraction method and application thereof in preparation of medicines for regulating intestinal flora and/or treating functional constipation |
abstract | The invention discloses a method for extracting durian peel polysaccharide for regulating intestinal flora, which comprises the steps of decocting durian peel with water, filtering, adding 95% ethanol into filtrate until the final concentration is 70 +/-5%, standing, collecting precipitate, dissolving in water, removing protein by a Sevage method, taking supernatant, adding 95% ethanol until the final concentration is 70 +/-5%, standing, washing precipitate, and freeze-drying to obtain the durian peel polysaccharide. The invention also discloses application of the durian peel polysaccharide in preparing a medicine for treating functional constipation. The invention is found through experiments that: the durian peel polysaccharide can obviously increase the content of Motilin (MTL), Gastrin (GAS) and substance P in serum and obviously reduce the content of somatostatin (SS); after being taken continuously, the medicine can obviously improve the relative abundance of Lachnospiraceae-NK4A136-group in intestinal tracts, reduce the relative abundance of the vibrio desulfurated, increase the defecation amount and the intestinal push rate and improve functional constipation. Description of the drawings: the durian peel polysaccharide is an ideal medicine for regulating intestinal flora and treating functional constipation. |
priorityDate | 2019-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 75.