http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110343057-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-14 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C303-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C303-38 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C303-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C311-14 |
| filingDate | 2019-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110343057-B |
| titleOfInvention | Synthesis method of amisulbrom |
| abstract | The invention provides a method for synthesizing cyclohexyl flusulfamide, which comprises the following steps: halogenating cyclohexanone to obtain 2-halogenated cyclohexanone and sulfiteReacting to obtain 2-oxo cyclohexyl sulfonate; and then reacting with oxalyl chloride and 2-trifluoromethyl-4-chloroaniline to obtain the cyclohexyl flusulfamide. In the invention, 2-halogenated cyclohexanone and sulfite are used for replacing cyclohexanone and sulfur trioxide-1, 4-dioxane compound, so that BaCl is avoided 2 Or Ba (OH) 2 Precipitating to remove SO 4 2‑ It is difficult to control the chemical reaction end point and the BaSO formed 4 The problem that the precipitate can not be utilized to become three wastes is solved, and the defects of corrosion, difficult storage, difficult operation, strong pungent peculiar smell, easy poisoning and the like of ammonia gas are overcome. The method has the advantages of mild reaction conditions, simple operation, high product purity and high yield; is suitable for large-scale industrial application. |
| priorityDate | 2019-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 81.