| abstract |
The invention discloses an antibacterial surface functionalized aniline oligomer nanofiber and a preparation method and application thereof. The functionalized aniline oligomer nanofiber is prepared by adding aniline oligomers into an organic solvent to be completely dissolved in an inert atmosphere of nitrogen or argon, adding degradable polymers dissolved in the same organic solution, uniformly stirring, adding a catalyst at 30-80 ℃ to react, and filtering, washing and drying to obtain an aniline oligomer-degradable polymer composite material; dissolving the composite material in an organic solvent, and performing electrostatic spinning to obtain aniline oligomer nanofiber; and (3) soaking the obtained nano-fiber after surface treatment in the same organic solution containing the antibacterial drugs, and washing and drying the nano-fiber to obtain the antibacterial fiber. The surface functionalized aniline oligomer nanofiber can promote cell adhesion, proliferation and differentiation in an external electromagnetic field environment, and has the characteristics of biodegradability, good biocompatibility, simple preparation method, simple synthesis and few byproducts. |