| abstract |
The invention provides a process for synthesizing phenylserine derivatives based on a fixed-bed reactor. The raw materials are uniformly mixed in a premixer and kept at a certain temperature, and then enter into contact with a catalyst from the upper part of the fixed bed to conduct Adol reaction, and the generated product passes through The outlet enters the first separator to remove a small amount of metal ions, and then flows through the second separator to separate products and by-products to obtain high-purity phenylserine derivative products. The solvent materials used and involved in the reaction can be recycled and applied after separation and concentration. The beneficial effects of the invention are as follows: (1) the reaction process is simple to operate, the whole process is flow-type reaction, high efficiency, and low time consumption; (2) the solvent and excess raw materials are applied mechanically, the three wastes are very little, and the green economy and environmental protection; (3) Low energy consumption, high unit output, suitable for scale-up production. |