http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110327495-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-14 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-222 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B33Y10-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3691 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3687 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3641 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3633 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B33Y10-00 |
filingDate | 2019-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-110327495-B |
titleOfInvention | Tissue engineering auricle form composite scaffold and preparation method thereof |
abstract | The invention relates to a tissue engineering auricle form composite stent and a preparation method thereof, wherein the method comprises the following steps: preparing cartilage tissue into cartilage acellular matrix powder, preparing gelatin or collagen suspension containing the cartilage acellular matrix, and constructing a three-dimensional digital model of human ear morphology through CT, MRI or laser scanning and computer-aided design; 3D printing a PCL substrate to prepare a three-dimensional human ear form auricle grid frame, and preparing a solid male die and a solid female die corresponding to the auricle form; fixing the three-dimensional human ear-shaped auricle grid framework between a solid male die and a solid female die, pouring prepared gelatin or collagen suspension of the cartilage acellular matrix, freezing after pouring, peeling the solid male die and the solid female die after freezing to obtain a three-dimensional freezing scaffold, immersing the three-dimensional freezing scaffold into a chemical cross-linking agent for cross-linking after freeze-drying, repeatedly washing and immersing by deionized water after cross-linking to remove the residual chemical cross-linking agent, and then carrying out vacuum freeze-drying to obtain the final three-dimensional auricle-shaped scaffold. |
priorityDate | 2019-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 60.