http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110327299-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-145 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-146 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-0008 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14 |
| filingDate | 2019-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110327299-B |
| titleOfInvention | Cationic polymer nanoparticle/hIL-22 BP gene compound for preventing and treating cancer and preparation method and application thereof |
| abstract | The invention relates to a cationic polymer nanoparticle/hIL-22 BP gene complex for preventing and treating cancer, a preparation method and application thereof, belonging to the field of biological pharmacy. The invention provides a cationic polymer nanoparticle/hIL-22 BP gene compound for preventing and treating cancers, which is obtained by compounding cationic polymer nanoparticles and a recombinant vector containing hIL-22BP coding genes through the charge adsorption effect. The compound can weaken the growth and proliferation signals of tumor cells by directly inducing the apoptosis of the tumor cells and blocking IL-22/IL-22R1 transmembrane signals, realize the inhibition effect on the proliferation of the tumor cells and achieve the effect of treating tumors. Animal experiments prove that the compound has the effect of inhibiting the growth of various tumors such as lung cancer, ovarian cancer, liver cancer, colon cancer and the like, has the average tumor inhibition rate of over 60 percent, and is a cancer treatment drug with wide application prospect. |
| priorityDate | 2019-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 252.