| abstract |
The invention relates to a dentin collagen fiber demineralization material and a preparation method and application thereof. Specifically, the present invention relates to a conjugate of water-soluble chitosan and an aminocarboxylic acid metal chelator, which is used for dental demineralization, preferably dentin demineralization. The invention also discloses a dentin collagen fiber demineralization material and a preparation method and application thereof. The material of the invention is composed of 0.5-1 parts by mass of water-soluble chitosan, 10-30 parts by mass of EDTA and 0.8-1.5 parts by mass. prepared by the compound. The present invention also relates to a dental demineralization composition comprising the conjugates and materials of the present invention. The conjugate, material and composition of the present invention can be used for dentin demineralization treatment before dental bonding repair, and when used as a dentin collagen demineralizer, it has excellent selective extrafibrous demineralization performance, good biological Compatibility, potent bacteriostasis and inhibition of endogenous matrix protease activity and extremely low cytotoxicity. |