http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110317204-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01P3-00 |
filingDate | 2019-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-110317204-B |
titleOfInvention | Pyrazolopyrimidinone derivative and preparation method and application thereof |
abstract | The invention discloses a pyrazolopyrimidinone derivative, wherein R 1 Is nicotinic acid, isonicotinic acid, 2-chloronicotinic acid, 6-chloronicotinic acid, 2-bromonicotinic acid, 6-bromonicotinic acid, 2-fluoronicotinic acid, 6-methoxynicotinic acid or 2-methoxynicotinic acid; r 2 Is hydrogen, fluorine, chlorine or methyl; r 3 Is hydrogen or methyl. 40 target compounds are synthesized in a chemical synthesis mode, and secondary structure optimization is further performed on the target compounds through chiral introduction, so that the prepared pyrazolopyrimidinone derivatives have broad-spectrum antifungal activity, and especially have obvious inhibitory activity on apple rot and apple ring rot; the application provides a foundation for developing a novel bactericide taking pyrazolopyrimidinone compound derivatives as active ingredients. |
priorityDate | 2019-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 102.