http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110314172-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_97f412a22f8f8f1195a7281ec378ed21 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-998 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2509-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-734 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-599 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0663 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0775 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-28 |
| filingDate | 2019-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8676c696f643060541d859752c93fb09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_676e828f33185bfed67745865efbd2cc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bfe84e15e7efdb0d0124ca4efa522fe2 |
| publicationDate | 2019-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110314172-A |
| titleOfInvention | A kind of cell preparation for treating spinal cord injury and preparation method thereof |
| abstract | The invention discloses a cell preparation for treating spinal cord injury and a preparation method. The preparation method of the preparation comprises the following steps: (1) obtaining mononuclear cells from healthy adult bone marrow by density gradient centrifugation; (2) Screening bone marrow mononuclear cells with immunomagnetic beads to obtain BMSCs; (3) performing flow sorting on the BMSCs obtained in step (2) to obtain TrkB+CD271+ cell subsets; (4) processing the obtained cell subsets, made into preparations. Based on the existing BMSC extraction technology, the present invention invents a method for using cell surface antigen markers to specifically separate cell subsets with strong nerve growth-promoting ability in a step-by-step manner, and obtains a new type of TrkB+ for treating spinal cord injury. The CD271+ BMSC subgroup preparation overcomes the problems of the current BMSC treatment of spinal cord injury with a small proportion of cells promoting nerve growth and poor efficacy. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115040693-A |
| priorityDate | 2019-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 43.