http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110305781-B

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filingDate 2019-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-110305781-B
titleOfInvention Microbial community co-cultivation device and evaluation method for in vitro activity evaluation of probiotics
abstract The invention relates to the field of activity evaluation of microecological preparations, in particular to a microbial community co-cultivation device and an activity evaluation method for in vitro activity evaluation of microecological preparations. The microbial community co-cultivation device includes a pure culture tube and a co-culture plate, the pure culture tube realizes anaerobic culture by connecting a deaerator; the co-culture plate is connected by a connecting tube and the pure culture tube; the co-culture plate A medium sampling port and a medium reinjection port are arranged on the upper wall of the medium sampling port, and the upper part of the medium sampling port and the medium reinjection port is provided with a small gas permeable rubber plug; the connecting pipe is provided with a communication valve. The co-cultivation system designed by the present invention realizes that aerobic bacteria, anaerobic bacteria and facultative bacteria are cultivated in the same culture system, that is, they are kept relatively independent and communicated with each other. Under the moderate shaking culture conditions, the culture medium between each culture chamber communicates slowly and interacts, simulating the survival state of microorganisms in the gut to the greatest extent.
priorityDate 2019-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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