http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110305142-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D489-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H17-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D489-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-00 |
filingDate | 2019-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-110305142-B |
titleOfInvention | Stereoselective synthesis method of 6 beta-hydroxymorphine derivative |
abstract | The invention discloses a stereoselective synthesis method of a 6 beta-hydroxymorphine derivative, which comprises the following steps: (i) reducing the compound shown in the formula VI into a compound shown in the formula VII by sodium borohydride in a hydrophilic organic solvent in the presence of catalytic amount of C1-C4 alkanoic acid; (ii) (ii) separating the compound of formula VII obtained in step (i) to obtain a compound of formula VIII; the definitions of the substituents in the formulae VI, VII and VIII are described in the specification. |
priorityDate | 2019-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 83.