http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110305100-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1007 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0043 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K11-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 |
| filingDate | 2019-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110305100-B |
| titleOfInvention | Near-infrared poly-hydrogen sulfide fluorescent probe and preparation method and application thereof |
| abstract | The invention relates to a near-infrared poly hydrogen sulfide fluorescent probe and a preparation method and application thereof, belonging to the field of chemistry and analysis and detection. The near-infrared fluorescence probe NIR-CPS for detecting the poly-hydrogen sulfide provided by the invention has the advantages of large Stokes shift (100nM), good selectivity, high sensitivity, low detection limit (18nM) and good biocompatibility. In the PBS buffer solution, the fluorescence intensity and the concentration of the poly-hydrogen sulfide present a good linear relationship, which indicates that the probe is suitable for quantitatively detecting the poly-hydrogen sulfide; the probe NIR-CPS also realizes the fluorescence imaging of the hydrogen sulfide in the MCF-7 cells; more importantly, the probe NIR-CPS also realizes the sensitive detection of endogenous poly hydrogen sulfide generated by lipopolysaccharide induction at the living body level, and has the advantages of quick response and stable fluorescence intensity. |
| priorityDate | 2019-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 84.