http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110305091-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D309-40 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D309-40 |
| filingDate | 2019-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110305091-B |
| titleOfInvention | Preparation method of Barosavir intermediate compound |
| abstract | The invention relates to a preparation method of a balosavir intermediate compound, which comprises the steps of taking 2-methyl-3-benzyloxy-4-oxo-4-hydropyran as an initial raw material, taking oxygen as an oxidant, carrying out an oxidation reaction in the presence of a nitrogen oxide catalyst to generate 3-benzyloxy-4-oxo-4-hydropyran-2-formaldehyde, carrying out one-step oxidation to obtain a product of 3-benzyloxy-4-oxo-4-hydropyran-2-carboxylic acid methyl ester, and optimizing the purification steps of the product; the method has the advantages of cheap and easily obtained raw materials, simple post-treatment steps, no additional production cost, capability of greatly reducing the production cost and the unit price of the product, contribution to expanding the research and development of various medical intermediates taking the product as the raw material, and good commercial value and industrial development potential. |
| priorityDate | 2019-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 80.