http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110305058-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bca206381ea8588aac4e4fb91cac4102 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-88 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-88 |
| filingDate | 2019-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9977eb955f720b794221356898f49762 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a3960752228dc4831ea9865c79d38bb |
| publicationDate | 2019-10-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-110305058-A |
| titleOfInvention | A kind of 4- bromine carbazole preparation method |
| abstract | The invention discloses a kind of 4- bromine carbazole preparation methods, in a reaction flask, the bromo- 6- fluoronitrobenzene of 2- is mixed with aniline, add triethylamine, open stirring, back flow reaction 8h, after reaction, water is added to extract reaction of going out, it filters, obtain brown-red solid, that is: 2- nitro -3- bromo- 1, 1 '-biphenyl, by 2- nitro -3- bromo- 1 obtained, 1 '-biphenyl and ethyl alcohol mixing, ferric trichloride and active carbon is added, open stirring, 80% hydrazine hydrate is added dropwise, it is added dropwise, again at reflux, stir 6h, through filtering, extraction, layering, washing, after distillation, obtain off-white powder, that is: 2- amino -3- bromo- 1, 1 '-biphenyl.The present invention obtains target compound, total yield of products is higher by fluorine nucleophilic displacement of fluorine, reduction, diazonium cyclization three-step reaction using raw material cheap and easy to get；Technological operation is simple, is suitable for large-scale production, is conducive to product competitiveness in the market. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114163417-A |
| priorityDate | 2019-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 73.