| abstract |
The invention belongs to the field of bone damage repairing biomedical materials, and particularly relates to a preparation method and application of an injectable bioactive glass containing demineralized bone matrix DBM. The injectable bioactive glass is composed of a solid phase and a liquid phase, wherein the solid phase is formed by mixing bioactive glass powder and DBM in proportion, and the mass ratio of the bioactive glass powder to DBM is 3. : 1; the liquid phase is a sodium carboxymethyl cellulose solution, and its concentration is 5~20wt%; the mass ratio of the solid phase to the liquid phase is 2:1~1:2; after the solid phase and the liquid phase are mixed according to the solid-liquid ratio into the syringe. The injectable bioactive glass containing demineralized bone matrix DBM provided by the present invention has good injection type, anti-collapse property, osteoconductivity, osteoinductivity, cell activity and good biodegradability, and is suitable for bone injury repair. |